Disruptores endocrinos e infertilidad masculina


Peribañez Garcia, Natalia


Endocrine disruptors (EDCS) have gained considerable attention in recent years, due to their potential to alter hormonal function and their association with a range of adverse consequences to male infertility. These substances are constantly present in the environment, through water, food, or products of daily consumption, it is for this reason that these compounds have aroused the concern of the scientific community and government institutions. These adverse effects have been demonstrated through exposure studies, with those carried out in humans being highly relevant, as is the case in the LIFE and EARTH studies. These studies have been the triggers for the creation of legislation in order to minimize the risks caused by these chemicals, as well as the main reasons for developing international studies that increase current knowledge about them, as well as research for the discovery of new chemical compounds. with endocrine disruption potential. Although the creation of these legislations regularly provokes ethical confrontations those in charge of writing these policies. However, although certain mechanisms of action of EDCS on the male reproductive system are known, there is an undeniable need for the development of new studies, focused not only on the risk assessment of disruptors, but on the creation of methods for prevention exposure of humans and wildlife, as well as in the characterization of the effects caused by these at low doses, under non-monotonical dose-response behaviors. Studies that, on the other hand, in some cases are already underway.



Carbó Banús, Marcel·lí


IQS SE - Undergraduate Program in Biotechnology