Elastomeric cardiopatch scaffold for myocardial repair and ventricular support

Authors

Chachques, J. C.; Lila, N.; Soler-Botija, C.; Martinez-Ramos, C.; Valles, A.; Autret, G.; Perier, M. C.; Mirochnik, N.; Monleon-Pradas, M.; Bayes-Genis, A.; Semino, C. E. 

Abstract

Prevention of postischaemic ventricular dilatation progressing towards pathological remodelling is necessary to decrease ventricular wall deterioration. Myocardial tissue engineering may play a therapeutic role due to its capacity to replace the extracellular matrix, thereby creating niches for cell homing. In this experimental animal study, a biomimetic cardiopatch was created with elastomeric scaffolds and nanotechnologies.

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Journal

European Journal of Cardio-Thoracic Surgery​, 2020, vol. 57, no. 3, p. 545–555

Date of publication

2019-09-20

DOI

https://doi.org/10.1093/ejcts/ezz252